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Monday, August 25, 2008

Scientists may have cured cancer last week.


Yep.

So, why haven’t the media picked up on it?

Here’s the deal. Researchers at the University of Alberta in Edmonton, Canada found a cheap and easy to produce drug that kills almost all cancers. The drug is dichloroacetate, and since it is already used to treat metabolic disorders, we know it should be no problem to use it for other purposes.

Doesn’t this sound like the kind of news you see on the front page of every paper?

The drug also has no patent, which means it could be produced for bargain basement prices in comparison to what drug companies research and develop.

Scientists tested DCA on human cells cultured outside the body where it killed lung, breast and brain cancer cells, but left healthy cells alone. Rats plump with tumors shrank when they were fed water supplemented with DCA.

Again, this seems like it should be at the top of the nightly news, right?

Cancer cells don’t use the little power stations found in most human cells - the mitochondria. Instead, they use glycolysis, which is less effective and more wasteful.

Doctors have long believed the reason for this is because the mitochondria were damaged somehow. But, it turns out the mitochondria were just dormant, and DCA starts them back up again.

The side effect of this is it also reactivates a process called apoptosis. You see, mitochondria contain an all-too-important self-destruct button that can’t be pressed in cancer cells. Without it, tumors grow larger as cells refuse to be extinguished. Fully functioning mitochondria, thanks to DCA, can once again die.

With glycolysis turned off, the body produces less lactic acid, so the bad tissue around cancer cells doesn’t break down and seed new tumors.

Here’s the big catch. Pharmaceutical companies probably won’t invest in research into DCA because they won’t profit from it. It’s easy to make, un-patented and could be added to drinking water. Imagine, Gatorade with cancer control.

So, the groundwork will have to be done at universities and independently funded laboratories. But, how are they supposed to drum up support if the media aren’t even talking about it?

All I can do is write this and hope Google News picks it up. In the meantime, tell everyone you know and do your own research.

This is a column of opinion written by Printz Executive Editor David McRaney. Comments can be sent to printz@usm.edu

Sunday, August 24, 2008

UNC researchers find MSG use linked to obesity

This is another reason to avoid Monosodium Glutamate (MSG). MSG is known to cause allergic reactions, headaches, cardiovascular problems among it's many side effects. MSG is found in Chinese restaurant food, and all processed food. The purpose is to "enhance" flavor of otherwise flavorless processed food. It provides absolutely no nutritional value. It is place in food to help the manufacturer...not the consumer. Later I will post specific foods to avoid and the different names manufacturers use to hide MSG on their labels.



CHAPEL HILL – People who use monosodium glutamate, or MSG, as a flavor enhancer in their food are more likely than people who don't use it to be overweight or obese even though they have the same amount of physical activity and total calorie intake, according to a University of North Carolina at Chapel Hill School of Public Health study published this month in the journal Obesity.

Researchers at UNC and in China studied more than 750 Chinese men and women, aged between 40 and 59, in three rural villages in north and south China. The majority of study participants prepared their meals at home without commercially processed foods. About 82 percent of the participants used MSG in their food. Those users were divided into three groups, based on the amount of MSG they used. The third who used the most MSG were nearly three times more likely to be overweight than non-users.

"Animal studies have indicated for years that MSG might be associated with weight gain," said Ka He, M.D., assistant professor of nutrition and epidemiology at the UNC School of Public Health. "Ours is the first study to show a link between MSG use and weight in humans."

Because MSG is used as a flavor enhancer in many processed foods, studying its potential effect on humans has been difficult. He and his colleagues chose study participants living in rural Chinese villages because they used very little commercially processed food, but many regularly used MSG in food preparation.

"We found that prevalence of overweight was significantly higher in MSG users than in non-users," He said. "We saw this risk even when we controlled for physical activity, total calorie intake and other possible explanations for the difference in body mass. The positive associations between MSG intake and overweight were consistent with data from animal studies."

As the percentage of overweight and obese people around the world continues to increase, He said, finding clues to the cause could be very important.

"The U.S. Food and Drug Administration and other health organizations around the world have concluded that MSG is safe," He said, "but the question remains – is it healthy?"

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Co-authors on the study included Liancheng Zhao and colleagues from Fu Wai Hospital and Cardiovascular Institute at the Chinese Academy of Medical Sciences in Beijing. Other researchers on this study were from Northwestern University in Chicago and the INTERMAP Cooperative Research Group.

The study is available online at: http://www.nature.com/oby/journal/v16/n8/full/oby2008274a.html

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